Related Experiment Video
Updated: Feb 4, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Algorithm to Predict Which Children With Chronic Abdominal Pain Are Low Suspicion for Significant Endoscopic Findings
Jacob A Mark1,2, Kristen Campbell3, Dexiang Gao3
11 Children's Hospital Colorado, Aurora, CO, USA.
Insights
A new diagnostic algorithm helps identify children with chronic abdominal pain (CAP). High-suspicion (HS) patients were more likely to have significant intestinal pathology found via endoscopy than low-suspicion (LS) patients.
Area of Science:
- Pediatric Gastroenterology
- Clinical Diagnostics
Background:
- Chronic abdominal pain (CAP) presents a significant challenge in pediatric care.
- Effective diagnostic strategies are needed to evaluate gastrointestinal causes of CAP.
Purpose of the Study:
- To develop and validate a diagnostic algorithm for pediatric CAP.
- To differentiate between low-suspicion (LS) and high-suspicion (HS) patients for significant intestinal pathology.
Main Methods:
- A diagnostic algorithm was created to categorize pediatric CAP patients.
- The algorithm was retrospectively applied to 150 outpatients with CAP.
- Endoscopic findings were analyzed for LS (n=99) and HS (n=51) groups.
Main Results:
- Significant diagnoses were found in 6% of LS patients versus 34% of HS patients (P < .0001).
- No celiac disease or inflammatory bowel disease was diagnosed in the LS group.
- The algorithm effectively stratified patients based on the likelihood of endoscopic findings.
Conclusions:
- The developed algorithm aids clinicians in approaching pediatric CAP.
- It helps families understand the probability of finding a cause for CAP through endoscopy based on suspicion level.
Abstract:
Chronic abdominal pain (CAP) is a common and challenging problem in pediatric primary and specialty care. We developed a diagnostic algorithm to organize workup for gastrointestinal causes of CAP and improve identification of patients who are low suspicion (LS) or high suspicion (HS) to have significant intestinal pathology identified with endoscopy. We retrospectively used this algorithm to categorize 150 outpatients with CAP as LS (n = 99) or HS (n = 51) and examined subsequent endoscopic findings for all patients. There were 6% significant diagnoses in the LS group compared with 34% in the HS group ( P < .0001). The LS group had no patients with celiac or inflammatory bowel disease. These results can be used to help a clinician approach CAP, and discuss with families the likelihood of endoscopy finding a cause for CAP based on LS or HS designation.
Related Concept Videos
Predicting Molecular Geometry
Trial and Error and Algorithm
Finding the Center of Gravity
Abdominal Aorta
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Pain
Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...

