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Updated: Feb 4, 2026

Spatial Molecular Imaging of the Glycome Using Mass Spectrometry
Published on: November 28, 2025
Understanding molecular mechanisms of disease through spatial proteomics
Sandra Pankow1, Salvador Martínez-Bartolomé1, Casimir Bamberger1
1Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, United States.
Abstract:
Mammalian cells are organized into different compartments that separate and facilitate physiological processes by providing specialized local environments and allowing different, otherwise incompatible biological processes to be carried out simultaneously. Proteins are targeted to these subcellular locations where they fulfill specialized, compartment-specific functions. Spatial proteomics aims to localize and quantify proteins within subcellular structures.
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