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Occupation and Risk of Kidney Cancer in Nordic Countries
Irmina Maria Michalek1, Jan Ivar Martinsen, Elisabete Weiderpass
1Faculty of Social Sciences, University of Tampere, Tampere, Finland (Drs Michalek, Pukkala), Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway (Martinsen, Drs Weiderpass, Kjaerheim), Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (Dr Weiderpass), Genetic Epidemiology Group, Folkhälsan Research Center and Faculty of Medicine, University of Helsinki, Helsinki, Finland (Dr Weiderpass), Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dr Weiderpass), Center for Epidemiology and Screening, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark (Dr Lynge), Icelandic Cancer Registry, Reykjavik, Iceland (Dr Tryggvadottir), Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland (Dr Pukkala).
Objective:
The aim of this study was to describe the occupational variation in the incidence of kidney cancer in the Nordic population.
Methods:
The population comprised of 14.9 million individuals included in censuses between 1960 and 1990. Standardized incidence ratios (SIRs) were calculated for each occupational group.
Results:
Significantly increased SIRs were observed in welders [1.24, 95% confidence interval (95% CI) 1.14 to 1.35], public safety workers (1.16, 95% CI 1.08 to 1.25), and seamen (1.16, 95% CI 1.07 to 1.26). Significantly decreased SIRs were found in laboratory assistants (0.76, 95% CI 0.60 to 0.94) and forestry workers (0.77, 95% CI 0.72 to 0.83).
Conclusion:
A relatively small variation in the incidence of malignancies of the kidney between occupational groups was found in the cohort. There is abundant room for further progress in determining the effect of smoking in particular occupational groups.
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