Related Experiment Video
Updated: Feb 4, 2026

A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats
Published on: December 2, 2016
Retraction Note: Cardiac structural remodeling in hypertensive cardiomyopathy
Si-Jia Sun1, Jia-Lu Yao1,2, Lang-Biao Xu1
1Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Insights
This study on hypertensive cardiomyopathy in pigs found no difference in left atrial wall fibrosis, contradicting previous findings. The authors are retracting the article due to unexplained inconsistencies in fibrosis measurements.
Area of Science:
- Cardiovascular Research
- Pathology
- Animal Models
Abstract:
The authors are retracting this article [1]. In their recent work the authors have found that the degree of fibrosis in the different walls of the left atrium in pigs with hypertensive cardiomyopathy is the same. Sirius Red staining (another method to test for fibrosis) showed that there was no difference between the different walls. The authors are unable to explain this inconsistency. All authors agree with this retraction.
Related Concept Videos
Nucleosome Remodeling
Nucleosome remodeling complex
Eukaryotic cells have specialized enzymes called ATP-dependent nucleosome remodeling enzymes. These enzymes...
Structure of Cardiac Muscles
Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
Cardiomyopathy II: Dilated Cardiomyopathy
Clot Retraction and Fibrinolysis
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy

