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Updated: Feb 4, 2026

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
Published on: June 28, 2019
Guest Editorial: Controversies in Fractional Flow Reserve
Maria Chiara Scali1, Doralisa Morrone2, Mario Marzilli2
1Cardiovascular Medicine Division, United Hospitals of Valdichiana, Montepulciano, Italy.
Abstract:
Fractional flow reserve (FFR) has been identified as the optimal diagnostic tool to identify significant coronary lesion. However, current evidence does not support this role. The optimal diagnostic strategy should give highly sensitive and specific results with lowest cost and accomplishing this task has been made more difficult in the era following the COURAGE trial.
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