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Cardio-oncology: A Focus on Cardiotoxicity
Athanasios Koutsoukis1, Argyrios Ntalianis1, Evangelos Repasos1
1Department of Clinical Therapeutics, National and Kapodistrian University of Athens Alexandra Hospital Athens, Greece.
Cardio-oncology addresses heart damage from cancer treatments. This review covers chemotherapy- and radiotherapy-induced cardiotoxicity, focusing on prevention and management strategies for cancer survivors.
Area of Science:
- Cardiology and Oncology
- Cardio-oncology as an emerging medical field
Background:
- Increasing cancer survival rates due to novel therapies.
- Potential cardiotoxicity associated with various cancer treatments, including anthracyclines, chemotherapy, and radiotherapy.
- Adverse impact of cardiotoxicity on cancer patient prognosis and quality of life.
Purpose of the Study:
- To review existing literature on chemotherapy- and radiotherapy-induced cardiotoxicity.
- To provide an overview of diagnostic imaging modalities for cardiotoxicity.
- To discuss current and emerging therapies for the prevention and management of cardiotoxicity.
Main Methods:
- Comprehensive literature search on cardiotoxicity induced by cancer therapies.
- Review of studies detailing imaging techniques for cardiotoxicity detection.
- Analysis of therapeutic strategies for cardiotoxicity prevention and treatment.
Main Results:
- Chemotherapy and radiotherapy pose significant risks of cardiotoxicity.
- Various imaging modalities aid in early identification of cardiac damage.
- Prevention and management strategies are essential for improving outcomes.
Conclusions:
- Cardio-oncology is vital for managing cardiovascular risks in cancer patients.
- Early detection and intervention are key to mitigating cardiotoxicity.
- Further research is needed to optimize prevention and treatment protocols.
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