Related Experiment Video
Updated: Feb 4, 2026

Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria
Published on: September 16, 2013
Bioactive nano-metal-organic frameworks as antimicrobials against Gram-positive and Gram-negative bacteria
Neha Bhardwaj1,2, Satish K Pandey1, Jyotsana Mehta1,2
1Central Scientific Instruments Organisation (CSIR-CSIO) , Sector 30 C , Chandigarh , 160030 , India . Email: dr.akashdeep@csio.res.in ; Tel: +91-172-2672236.
Abstract:
More effective antibiotics are needed to overcome the problem of multidrug resistance. The antibacterial efficacies of three Zn-based nano metal-organic frameworks (nMOFs) - IRMOF-3, MOF-5, and Zn-BTC - were explored, both alone and as mixtures with ampicillin and kanamycin. When tested against Escherichia coli, Staphylococcus aureus, Staphylococcus lentus, and Listeria monocytogenes, the nMOF/drug mixtures demonstrated synergistic (IRMOF-3/kanamycin) or additive (other nMOF/drug combinations) effects compared with the nMOFs or antibiotics alone. Zn-Based nMOFs can reduce the burden of the new discovery of antimicrobial pharmaceuticals by increasing the potency of existing antibiotics.
More Related Videos
Related Concept Videos
Gram-negative Bacterial Protein Secretion Systems
Positive, Negative, and Zero Work
Positive and Negative Feedback Loops
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Bonding in Metals
Antimicrobial Effectiveness

