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Designing humans: A human rights approach.

S Matthew Liao1

  • 1Center for Bioethics, New York University, New York, USA.

Bioethics
|October 13, 2018
PubMed
Summary
This summary is machine-generated.

New genomic technologies offer precise reproductive genetic engineering for desired traits. A human rights approach provides a plausible ethical framework, establishing a baseline for permissible interventions.

Keywords:
CRISPRdesigner babiesgene editinggene therapygenetic enhancementreproductive genetic engineering

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Area of Science:

  • Bioethics
  • Genomic Engineering
  • Human Rights Law

Background:

  • Advancements in genomic technologies like CRISPR-Cas9, mitochondrial replacement, and in vitro gametogenesis are nearing clinical application.
  • These technologies raise ethical questions regarding the engineering of specific traits in offspring, such as intelligence and athleticism.

Purpose of the Study:

  • To propose and evaluate a novel human rights approach to the ethics of reproductive genetic engineering.
  • To establish a foundational ethical framework for assessing the permissibility of reproductive genetic interventions.

Main Methods:

  • The study outlines a human rights framework grounded in the principles of equal moral status and the right to conditions for a good life.
  • It involves a comparative analysis of the proposed human rights approach against existing ethical frameworks, including libertarian, perfectionist, and life worth living perspectives.

Main Results:

  • The human rights approach establishes a lower bound for the ethical permissibility of reproductive genetic engineering.
  • This framework offers a more plausible and novel method for evaluating the ethical considerations of these advanced reproductive technologies compared to alternative ethical theories.

Conclusions:

  • The human rights approach provides a robust ethical foundation for navigating the complexities of reproductive genetic engineering.
  • It emphasizes fundamental human rights as a crucial benchmark for assessing the acceptability of genetic interventions aimed at trait selection.