Related Experiment Video

Updated: Feb 4, 2026

Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing
08:19

Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing

Published on: July 7, 2020

11.4K

Know your enemy: managing resistant Gram-negative infections

Christian Eckmann1, Laura J Rojas2,3, Sue Lyon4

  • 1Department of General, Visceral & Thoracic Surgery, Klinikum Peine, Academic Hospital of Medical University Hannover, Germany.

Future Microbiology
|October 13, 2018
PubMed

Insights

Multidrug-resistant Gram-negative bacteria, including Klebsiella, Acinetobacter, and Pseudomonas, pose a significant global challenge. Effective management of these severe infections is critical for all healthcare settings.

Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Gram-negative bacteria like Klebsiella, Acinetobacter, and Pseudomonas are major causes of severe hospital-acquired infections.
  • Increasing antimicrobial resistance in these pathogens limits treatment options, posing a global health threat.

Framework:

  • The 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2018) addressed critical challenges in infectious disease management.
  • Discussions focused on the growing problem of multidrug-resistant Gram-negative bacteria.

Implementation:

  • The congress highlighted the urgent need for strategies to combat infections caused by resistant bacteria.
  • Sharing of knowledge and best practices among infectious disease specialists was a key focus.

Implications:

  • Effective management of these infections is crucial for patient outcomes and healthcare system sustainability.
  • Findings from ECCMID 2018 have broad implications for hospitals and clinical microbiology worldwide.
Keywords:
Antibiotic resistanceAntimicrobialECCMIDEnterobacteriaceaeGram-negativeMultidrug resistanceStewardship

More Related Videos

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

7.0K
Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria12:57

Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria

Published on: September 16, 2013

32.8K

Related Concept Videos

Gram-negative Bacterial Protein Secretion Systems01:17

Gram-negative Bacterial Protein Secretion Systems

Gram-negative bacteria utilize sophisticated protein secretion systems to transport proteins across their double-membrane envelope into the extracellular environment or host cells. Based on their mechanism of action, these systems are classified into one-step and two-step pathways.One-Step Secretion Systems (Types I, III, IV, and VI)One-step secretion systems bypass the periplasm entirely, forming a continuous channel that spans both the inner and outer membranes:Type I Secretion System (T1SS):...
918
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
475
Negative Regulator Molecules01:23

Negative Regulator Molecules

Positive regulators allow a cell to advance through cell cycle checkpoints. Negative regulators have an equally important role as they terminate a cell’s progression through the cell cycle—or pause it—until the cell meets specific criteria.
38.5K
Positive, Negative, and Zero Work00:58

Positive, Negative, and Zero Work

Work is done on an object when energy is transferred to the object. In other words, work is done when a force acts on a body that undergoes a displacement from one position to another. By definition, the work done by a force is the integral of the force with respect to the displacement along its path. Forces can vary as a function of position, and displacements can occur along various paths between two points. The magnitude of a force multiplied by the cosine of the angle that the force makes...
22.2K
Resistivity01:22

Resistivity

When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.6K
Resistance01:19

Resistance

When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
6.0K