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Related Concept Videos

Weak Base Solutions03:21

Weak Base Solutions

25.2K
Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
25.2K
Strong Acid and Base Solutions03:22

Strong Acid and Base Solutions

35.7K
A strong acid is a compound that dissociates completely in an aqueous solution and produces a concentration of hydronium ions equal to the initial concentration of acid. For example, 0.20 M hydrobromic acid will dissociate completely in water and produces 0.20 M of hydronium ions and 0.20 M of bromide ions.
35.7K
Leveling Effect and Non-Aqueous Acid-Base Solutions02:11

Leveling Effect and Non-Aqueous Acid-Base Solutions

9.5K
This lesson defines the leveling effect in acidic and basic solutions and its role in aqueous and non-aqueous solutions. It is essential to understand the competing nature of various species in a chemical system.
The Leveling Effect of a Solvent
A generic acid (HA) reacts with the generic base (B-) to yield the corresponding conjugate base (A-) and conjugate acid (HB):
9.5K
Solution Composition During Acid/Base Titrations01:17

Solution Composition During Acid/Base Titrations

1.6K
The titration of a weak acid with a strong base results in the formation of water and the conjugate base of the acid. For instance, titrating acetic acid with sodium hydroxide leads to the formation of water and sodium acetate. A solution of acetic acid and sodium acetate constitutes a buffer whose relative concentration at different stages of the titration is indicated by the α values, which represent percentages of the weak acid and its conjugate base.
The α0 and α1 values...
1.6K
Determining the pH of Salt Solutions04:08

Determining the pH of Salt Solutions

48.1K
The pH of a salt solution is determined by its component anions and cations. Salts that contain pH-neutral anions and the hydronium ion-producing cations form a solution with a pH less than 7. For example, in ammonium nitrate (NH4NO3) solution, NO3− ions do not react with water whereas NH4+ ions produce the hydronium ions resulting in the acidic solution.  In contrast, salts that contain pH-neutral cations and the hydroxide ion-producing anions form a solution with a pH greater than 7. For...
48.1K
Ideal Solutions02:24

Ideal Solutions

22.4K
According to Raoult’s law, the partial vapor pressure of a solvent in a solution is equal or identical to the vapor pressure of the pure solvent multiplied by its mole fraction in the solution. However, Raoult's Law is only valid for ideal solutions. For a solution to be ideal, the solvent-solute interaction must be just as strong as a solvent-solvent or solute-solute interaction. This suggests that both the solute and the solvent would use the same amount of energy to escape to the...
22.4K

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Updated: Feb 4, 2026

Scalable Solution-processed Fabrication Strategy for High-performance, Flexible, Transparent Electrodes with Embedded Metal Mesh
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SNPSelect: A scalable and flexible targeted sequence-based genotyping solution.

René C J Hogers1, Marjo de Ruiter1, Koen H J Huvenaars1

  • 1Keygene NV, Wageningen, Gelderland, The Netherlands.

Plos One
|October 13, 2018
PubMed
Summary
This summary is machine-generated.

KeyGene SNPSelect offers a flexible, targeted genotyping solution for plant breeding. This technology enables rapid, cost-effective, and highly accurate Single Nucleotide Polymorphism (SNP) analysis, accelerating the development of new crop varieties.

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Area of Science:

  • Plant genetics and breeding
  • Molecular biology
  • Genomics

Background:

  • Molecular markers significantly accelerate crop variety development.
  • Single Nucleotide Polymorphism (SNP) genotyping is crucial for various genetic studies including association, LD, and QTL mapping.

Purpose of the Study:

  • To introduce KeyGene SNPSelect, a scalable and flexible multiplexed, targeted sequence-based genotyping solution.
  • To demonstrate the adaptability and efficiency of the SNPSelect technology for plant breeding applications.

Main Methods:

  • Designed a 1,056-plex maize assay for genotyping 374 samples from diverse populations.
  • Assembled subsets of informative SNPs into 384-plex and 768-plex assays for further genotyping.
  • Evaluated assay performance based on call rates and reproducibility.

Main Results:

  • Achieved high average call rates (88.1% to 99.4%) and reproducibility (98.2% to 99.9%) across different multiplex assay sizes.
  • Demonstrated flexibility by easily modifying multiplex assay content.
  • Completed the SNPSelect workflow from DNA sample to genotype data in under three days.

Conclusions:

  • KeyGene SNPSelect provides a cost-efficient, highly informative, and rapid genotyping solution.
  • The technology is well-suited to meet targeted genotyping needs in plant breeding.
  • SNPSelect offers a competitive option for accelerating the development of improved crop varieties.