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[Clinical and demographic features of patients with stroke and atrial fibrillation]

D M Akpanova1, S F Berkinbayev1, A T Mussagaliyeva1

  • 1Scientific and Research Institute of Cardiology and Internal Diseases, Almaty.

Kardiologiia
|October 13, 2018
PubMed

Insights

Atrial fibrillation (AF) affects over 10% of stroke patients, significantly increasing in-hospital mortality risk. Few AF patients received preventive therapy, highlighting a critical gap in stroke prevention strategies.

Area of Science:

  • Cardiology
  • Neurology
  • Public Health

Background:

  • Stroke is a leading cause of death and disability globally.
  • Atrial fibrillation (AF) is a major independent risk factor for ischemic stroke.
  • Stroke prevention remains a significant medical and societal challenge.

Purpose of the Study:

  • To determine the prevalence of atrial fibrillation (AF) in patients hospitalized with stroke or transient ischemic attack (TIA).
  • To assess the use of anticoagulant therapy in AF patients with stroke/TIA prior to hospitalization.
  • To evaluate the in-hospital mortality rates associated with AF in stroke/TIA patients.

Main Methods:

  • Retrospective analysis of 7,921 patient case reports from January 2013 to December 2015.
  • Selection of 849 case reports for patients diagnosed with both acute cerebrovascular disease/TIA and AF.
  • Utilized CHA2DS2‑VASc scale for risk stratification and analyzed mortality data.

Main Results:

  • The incidence of AF among stroke/TIA patients was 10.72%.
  • A high percentage (93.8%) of AF patients were classified as high-risk for thromboembolic complications.
  • Only 4.7% of AF patients received preventive therapy.
  • In-hospital mortality was significantly higher in patients with AF (15.78%) compared to those without AF (7.01%).

Conclusions:

  • Atrial fibrillation is a significant risk factor for in-hospital mortality in stroke/TIA patients.
  • There is a substantial gap in the preventive therapy uptake for thromboembolic complications in AF patients with stroke/TIA.
  • Improved screening and management of AF in stroke patients are crucial for reducing mortality.
Abstract

Keywords:
atrial fibrillation, stroke, oral anticoagulants

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