Related Experiment Video
Updated: Feb 4, 2026
04:01
Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
1.5K
Relationship between ultrasonographic and pathologic calcification patterns in papillary thyroid cancer.
Bu Kyung Kim1, Eun Mi Lee1, Jeong Hoon Kim2
1Department of Internal Medicine.
Medicine
|October 14, 2018
Summary
Ultrasonographic microcalcification in thyroid nodules often indicates the presence of psammoma bodies, a poor prognostic factor in papillary thyroid cancer (PTC). This finding suggests ultrasound microcalcification can predict PTC aggressiveness.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Ultrasonographic microcalcification is linked to papillary thyroid cancer (PTC).
- Pathologic psammoma bodies are associated with poor prognosis in PTC.
- The correlation between ultrasonographic microcalcifications and pathologic psammoma bodies is not well understood.
Purpose of the Study:
- To evaluate the relationship between ultrasonographic (US) calcification types and pathologic calcification features.
- To determine the consistency between US-observed calcifications and pathologic findings.
Main Methods:
- US calcifications were categorized into microcalcification (MC) and non-microcalcification (non-MC) types.
- Pathologic calcifications were classified as psammoma bodies, stromal calcifications, or ossifications.
- Logistic regression analysis was used to assess the predictive value of US calcification types.
Main Results:
- Of 411 nodules, 38.9% showed US calcification.
- Larger pathologic calcifications correlated with increased US calcification presence (ossification > stromal > psammoma).
- US microcalcification (MC) was consistently associated with psammoma bodies, while non-MC was linked to ossification.
Conclusions:
- Ultrasonographic microcalcification is consistent with the presence of pathologic psammoma bodies.
- US identification of microcalcification may serve as a prognostic indicator for papillary thyroid cancer aggressiveness.
Related Concept Videos
01:11Papillary Dermis
5.7K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
5.7K
02:12Relationship Formation
46.2K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
46.2K
01:28Ending Relationships
189
The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
189
01:23The Thyroid Gland
7.7K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.7K
01:27Relationship Growth
220
Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...
220
01:18Functions of Thyroid Hormones
5.6K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.6K