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Updated: Feb 4, 2026

Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
Pain management of chronic wounds: Diabetic ulcers and beyond
Stavroula A Paschou1, Maria Stamou2, Hubert Vuagnat3
1Division of Endocrinology and Diabetes, "Aghia Sophia" Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Abstract:
Patients who suffer from ulcers often experience pain of sufficient severity to reduce their quality of life. The aim of this review article is to collect, analyze and qualitatively resynthesize information regarding the definition and prevalence of ulcer pain, the pathophysiology of such pain, its assessment, and the optimal systemic and topical treatments. Early identification and prompt treatment are key to pain management. Further management should focus on appropriate dressing as much as on pain medication. The goal is to provide maximum relief with minimum side-effects.
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