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Functional MRI in Idiopathic Parkinson's Disease
Massimo Filippi1, Sarasso Elisabetta2, Noemi Piramide3
1Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
International Review of Neurobiology
|October 14, 2018
Summary
Functional MRI (fMRI) reveals altered brain connectivity in Parkinson's disease (PD). This neuroimaging technique offers potential for early detection and monitoring treatment effects in PD patients.
Area of Science:
- Neuroscience
- Medical Imaging
Background:
- Functional MRI (fMRI) is extensively used to investigate brain connectivity in idiopathic Parkinson's disease (PD).
- fMRI studies have enhanced understanding of both motor and non-motor symptoms in PD.
Purpose of the Study:
- To summarize the utility of fMRI in understanding Parkinson's disease.
- To highlight the potential clinical applications of fMRI in PD management.
Main Methods:
- Review of existing functional MRI studies in Parkinson's disease patients.
- Analysis of fMRI data during rest and task-based conditions.
Main Results:
- fMRI has identified abnormal brain connectivity patterns in PD.
- Studies show fMRI's role in understanding diverse PD symptoms.
Conclusions:
- fMRI shows promise for early PD detection.
- fMRI measures may predict clinical changes and track therapeutic effects.
- Clinical translation of fMRI in PD is advancing.