Related Experiment Video

Updated: Feb 4, 2026

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
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Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors

Published on: February 28, 2021

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Technique Pinpoints Oncogenic BRCA1 Mutations

    Cancer Discovery
    |October 14, 2018
    PubMed
    Summary

    Researchers induced thousands of BRCA1 gene mutations in human cells. Over 20% of these single-nucleotide variants were found to be potentially cancer-causing, impacting cancer research.

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