Parvovirus infections in childhood

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Updated: Sep 23, 2026

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems
13:47

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems

Published on: April 23, 2012

R Listernick

    Pediatric Dermatology
    |December 1, 1986
    PubMed

    Insights

    Human parvovirus (HPV) infections cause erythema infectiosum and aplastic crises in children. Further research is needed to understand HPV

    Area of Science:

    • Virology
    • Pediatrics
    • Obstetrics

    Background:

    • Human parvovirus (HPV) is linked to various clinical conditions.
    • It is the causative agent of erythema infectiosum (fifth disease).
    • HPV is a primary cause of aplastic crises in pediatric patients with sickle cell disease and other hemolytic anemias.

    Purpose of the Study:

    • To summarize the clinical associations of Human parvovirus infections.
    • To highlight the role of HPV in pediatric hematologic crises and erythema infectiosum.
    • To identify areas for further research regarding intrauterine HPV infections and fetal outcomes.

    Main Methods:

    • Literature review of studies on Human parvovirus infections.
    • Clinical case analysis of patients with HPV-associated syndromes.
    • Review of documented cases of intrauterine HPV infection.

    Main Results:

    • HPV infections are associated with erythema infectiosum and aplastic crises.
    • Acute symmetric polyarthritis has been linked to recent HPV infection.
    • Two stillborn infants with confirmed HPV infections have been identified.

    Conclusions:

    • Human parvovirus infections present with diverse clinical manifestations.
    • The association between HPV, intrauterine infection, and fetal damage requires additional investigation.
    • Further research is warranted to elucidate the full spectrum of HPV's impact on pregnancy and fetal development.

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