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Successful Transplantation of "Black Kidneys" Due to Myoglobin Nephropathy
1Organ Transplant Center and Department of Pathology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Abstract:
Four kidneys from 2 young donors suffering from rhabdomyolysis were rejected for transplantation at the time of procurement because of their severely bruised and black gross appearance. A frozen section revealed a focal tubular injury filled with granular pigmented casts which an immunohistochemistry confirmed to be myoglobin. The 4 kidneys were transplanted successfully and all recipients recovered normal renal function with no delay. These cases indicate that kidneys with patchy black gross appearance caused by myoglobin casts secondary to rhabdomyolysis is not a contraindication for transplantation.