Whole-Body Imaging in Multiple Myeloma

Area of Science:

• Radiology
• Oncology
• Medical Imaging

Background:

• Multiple myeloma (MM) is a hematologic malignancy.
• Accurate diagnosis and response assessment are crucial for MM management.
• Imaging plays a key role in staging and monitoring MM.

Purpose of the Study:

• To outline current international imaging guidance for multiple myeloma.
• To summarize evidence on whole-body MRI (WB-MRI) in MM diagnosis and response assessment.
• To provide practical recommendations for WB-MRI protocols.

Main Methods:

• Review of current international imaging guidelines for MM.
• Synthesis of evidence on WB-MRI for MM diagnosis and response assessment.
• Inclusion of diffusion-weighted imaging (DWI) in WB-MRI protocols.

Main Results:

• WB-MRI is valuable for diagnosing multiple myeloma.
• WB-MRI aids in assessing treatment response in MM patients.
• Specific WB-MRI protocols, including DWI, are recommended.

Conclusions:

• WB-MRI is an essential tool in the management of multiple myeloma.
• Adherence to suggested protocols can optimize diagnostic accuracy and response assessment.
• Understanding pearls, pitfalls, and variants enhances the utility of WB-MRI in MM.