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Voxel-size dependent quantitative susceptibility mapping of blood vessel networks: A simulation study
Lukas R Buschle1, Thomas Kampf2, Felix T Kurz3
1German Cancer Research Center (DKFZ), Department of Radiology (E010), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Heidelberg University Hospital, Department of Neuroradiology, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Heidelberg University, Faculty of Physics and Astronomy, Im Neuenheimer Feld 227, 69120 Heidelberg, Germany.
Abstract:
Quantitative susceptibility mapping provides a measure for the local susceptibility within a voxel in magnetic resonance imaging (MRI). So far, theoretical and numerical studies focus on the assumption of a constant susceptibility inside each MR voxel. For blood vessel networks, however, susceptibility differences between blood and surrounding tissue occur on a much smaller length scale than the typical voxel size in routine MRI. In this work, the dependency of the quantitative susceptibility value on vessel size and voxel size is analyzed.
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