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Updated: Feb 4, 2026
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Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
Published on: August 24, 2018
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Titanium mesh associated with rhBMP-2 in alveolar ridge reconstruction
G S Trento1, P H A Carvalho1, D V Macedo1
1Department of Diagnosis and Surgery, Division of Oral and Maxillofacial Surgery, Dental School at Araraquara - UNESP, Araraquara SP, Brazil.
International Journal of Oral and Maxillofacial Surgery
|October 16, 2018
Summary
Titanium mesh combined with recombinant human bone morphogenetic protein (rhBMP) offers a successful method for alveolar ridge reconstruction. This approach shows high rehabilitation success rates with minimal local complications in patients.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Biomaterials Engineering
Background:
- Alveolar ridge defects present challenges for dental implant rehabilitation.
- Titanium mesh and recombinant human bone morphogenetic protein (rhBMP) are utilized in bone regeneration.
- Evidence on the combined efficacy of these materials for alveolar reconstruction requires synthesis.
Purpose of the Study:
- To systematically review the literature on the use of titanium mesh with rhBMP for alveolar ridge reconstruction.
- To evaluate the success rates and complication profiles of this combined treatment modality.
Main Methods:
- A systematic literature search was conducted in PubMed, Scopus, and Cochrane databases up to June 2017.
- Inclusion criteria focused on human studies (RCTs, prospective/retrospective studies, case series).
- Eleven studies involving 106 patients were selected for analysis.
Main Results:
- The combined use of rhBMP and titanium mesh demonstrated high success rates for alveolar ridge augmentation, ranging from 93.4% to 100%.
- Grafts were performed in 74 maxillary and 22 mandibular cases.
- The most common complications were suture dehiscence and mesh exposure, without significant graft loss.
Conclusions:
- The combination of rhBMP and titanium mesh is a viable and effective method for alveolar ridge reconstruction.
- This technique achieves high success rates in dental rehabilitation.
- Local complications are generally manageable and do not typically lead to graft failure.
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