Managing fetal growth restriction: surveillance tests and their interpretation

The main challenges in pregnancies affected by fetal growth restriction consist in identifying signs of disease progression and determining the appropriate timing of delivery. The risk of continuing the pregnancy must be balanced with the risk of prematurity, which depends on gestational age. To allow appropriate monitoring of the growth-restricted fetus, several surveillance tests are available. These include ultrasound Doppler velocimetry of feto-placental vessels, cardiotocography, and amniotic fluid evaluation. It is well known that the combination of tests performs better than each test alone to predict fetal deterioration. The interpretation of test results depends on the gestational age and on the nature of the growth disorder (early- vs. late-onset disease). Appropriate knowledge on the surveillance tests interpretation and the frequency at which they need to be performed is crucial in managing fetal growth restriction, in order to produce better outcome and prevent stillbirth, and at the same time to avoid unnecessary interventions.