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Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition)
Jian Zhou1, Hui-Chuan Sun1, Zheng Wang1
1Department of Liver Surgery & Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, China.
Insights
This guideline provides expert recommendations for hepatocellular carcinoma (HCC) surveillance, diagnosis, staging, and treatment in China. It aims to improve patient outcomes for this prevalent liver cancer in the region.
Area of Science:
- Oncology
- Hepatology
- Public Health
Background:
- Hepatocellular carcinoma (HCC) is a major health concern in China, being the fourth most common malignancy and third leading cause of cancer death.
- High prevalence of chronic hepatitis B infection contributes significantly to HCC incidence in China.
- HCC poses a substantial threat to the health and lives of the Chinese population.
Purpose of the Study:
- To present official recommendations from China's National Health and Family Planning Commission for HCC management.
- To provide guidance on surveillance, diagnosis, staging, and treatment of HCC specific to the Chinese context.
Main Methods:
- Development of guidelines by over 50 Chinese HCC experts, including surgeons, oncologists, hepatologists, and radiologists.
- Recommendations based on current evidence, expert consensus, and consideration of benefits, harms, and cost-effectiveness.
- Inclusion of the Chinese staging system for HCC patient management.
Main Results:
- Established a comprehensive guideline for HCC surveillance, diagnosis, staging, and treatment in China.
- Incorporated the specific Chinese staging system for HCC.
- Provided evidence-based recommendations to optimize patient outcomes.
Conclusions:
- The guideline offers a standardized approach to HCC management in China.
- Expert consensus and current evidence form the basis of these recommendations.
- Implementation of this guideline is expected to improve outcomes for Chinese patients with HCC.
Background:
Hepatocellular carcinoma (HCC) (about 85-90% of primary liver cancer) is particularly prevalent in China because of the high prevalence of chronic hepatitis B infection. HCC is the fourth most common malignancy and the third leading cause of tumor-related deaths in China. It poses a significant threat to the life and health of Chinese people.
Summary:
This guideline presents official recommendations of the National Health and Family Planning Commission of the People's Republic of China on the surveillance, diagnosis, staging, and treatment of HCC occurring in China. The guideline was written by more than 50 experts in the field of HCC in China (including liver surgeons, medical oncologists, hepatologists, interventional radiologists, and diagnostic radiologists) on the basis of recent evidence and expert opinions, balance of benefits and harms, cost-benefit strategies, and other clinical considerations.
Key Messages:
The guideline presents the Chinese staging system, and recommendations regarding patients with HCC in China to ensure optimum patient outcomes.
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