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Updated: Feb 3, 2026

Reverse Total Shoulder Arthroplasty
Published on: July 5, 2011
Significance of Perioperative Tests to Diagnose the Infection in Revision Total Shoulder Arthroplasty
Shahryar Ahmadi1,2, Thomas M Lawrence1,2, Shawn Sahota1,2
1Research performed at Mayo Clinic, Rochester, USA.
Background:
The purpose of this study was to evaluate the value of perioperative tests for the diagnosis of infection in revision shoulder arthroplasty.
Methods:
A retrospective analysis was performed on 537 shoulder arthroplasties (429 patients) that underwent revision shoulder arthroplasty at our institution. Periprosthetic tissue cultures were positive in 169/537 surgeries.
Results:
White-blood cell count (WBC) was elevated in 3.8% revision arthroplasties. Erythrocyte sedimentation rate (ESR) was elevated in 23.1% revision arthroplasties. The C-reactive protein (CRP) was elevated in 20.8% revision arthroplasties. Bone scans (technetium, indium) were performed on 9.9% patients and it was positive for osteomyelitis in just one revision arthroplasty. Intra-operative pathology was read as consistent with acute inflammation in 11.9% revision arthroplasties. The positive and negative predictive values for intra-operative pathology were 56.7% and 71.6% respectively.
Conclusion:
All of the perioperative tests had a high specificity and negative predictive value, but low sensitivity and positive predictive value.
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