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Related Experiment Video

Updated: Feb 3, 2026

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

Stroke-related epilepsy.

A M Feyissa¹, T F Hasan², J F Meschia¹

¹Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.

European Journal of Neurology

|October 16, 2018

Summary

This summary is machine-generated.

Stroke-related epilepsy (STRE) is a growing concern, particularly in the elderly, despite advances in stroke care. While often manageable with medication, some cases become drug-resistant, necessitating further research into prevention and treatment strategies.

Keywords:

epilepsy epileptogenesis focal epilepsy post-stroke epilepsy stroke symptomatic epilepsy

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Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

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Published on: December 18, 2016

Area of Science:

Neurology
Epileptology
Geriatrics

Background:

Stroke is a significant cause of epilepsy, accounting for 10% of all epilepsy cases and 55% of new seizures in the elderly.
Advances in acute stroke therapy have increased patient survival, leading to a rise in stroke-related epilepsy (STRE).
Clinical distinctions are made between early (within 7 days) and late (beyond 7 days) seizures post-stroke, based on differing presumed pathophysiological mechanisms.

Purpose of the Study:

To summarize the current understanding of stroke-related epilepsy (STRE), including its prevalence, pathophysiology, prognosis, and treatment challenges.
To highlight the need for further research in the primary and secondary prevention of STRE.
To emphasize the requirement for robust clinical prediction models for STRE.

Main Methods:

Review of existing clinical studies and literature on stroke-related epilepsy.
Analysis of the distinction between early and late post-stroke seizures.
Evaluation of the efficacy and tolerability of antiepileptic drugs in STRE management.

Main Results:

STRE has a generally good prognosis and is often controlled by antiepileptic drugs.
Up to 25% of STRE cases are resistant to drug treatment.
STRE is associated with increased morbidity, prolonged hospitalization, greater disability, and higher healthcare resource utilization.

Conclusions:

Further controlled trials are essential to investigate the prevention of STRE and to establish evidence-based treatment guidelines for antiepileptic drugs.
Development of robust pre-clinical and clinical prediction models is crucial for devising interventions to prevent the transition of infarcted brain tissue into an epileptic focus.