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Nutritional effect on age-related cataract formation and progression
Ruti Sella1, Natalie A Afshari
1Department of Ophthalmology, Shiley Eye Institute, University of California San Diego, La Jolla, California, USA.
Current Opinion in Ophthalmology
|October 16, 2018
Summary
A diet rich in fruits and vegetables, and high intake of vitamins A, C, D, E, and K1 may reduce the risk of age-related cataract. Further research is needed to confirm the benefits of nutritional supplements.
Area of Science:
- Ophthalmology
- Nutritional Science
- Gerontology
Background:
- Cataract formation and progression are multifactorial processes.
- Nutrition plays a potential role in modulating cataract development.
Purpose of the Study:
- To summarize current evidence on nutrients associated with cataract pathogenesis.
- To evaluate the impact of dietary intake on cataract risk and progression.
Main Methods:
- Comprehensive review of peer-reviewed publications.
- Analysis of observational studies and meta-analyses.
- Evaluation of interventional study data.
Main Results:
- Observational studies show a correlation between nutrient intake and age-related cataract.
- Meta-analyses suggest benefits from high intake of vitamins A, C, and E.
- Vitamins K1 and D may offer protection; Mediterranean diet and dairy intake showed no significant effect in some studies.
Conclusions:
- Diets rich in fruits, vegetables, and specific vitamins (A, C, D, E, K1) may lower cataract risk.
- More research is needed to confirm long-term benefits of nutritional supplements across diverse nutritional statuses.
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