[Left ventricular hypertrophy : how to identity the cause ?]

Area of Science:

• Cardiology
• Medical Diagnostics

Background:

• Left ventricular hypertrophy (LVH) signifies increased left ventricular mass, often linked to pressure/volume overload or primary myocardial diseases.
• LVH prevalence rises with age, posing a significant risk factor for cardiovascular events and mortality.
• Accurate diagnosis of the underlying cause of LVH is crucial for effective patient management, risk stratification, and treatment.

Purpose of the Study:

• To review recent diagnostic advancements in identifying the causes of left ventricular hypertrophy.
• To highlight how these advances facilitate improved medical management for patients with LVH.

Main Methods:

• Utilizing multimodal imaging techniques for comprehensive cardiac assessment.
• Employing genetic analysis to identify inherited cardiomyopathies contributing to LVH.
• Integrating clinical, electrical, and biological indicators to detect underlying conditions.

Main Results:

• Multimodal imaging, genetics, and clinical "red flags" enable precise LVH cause identification.
• Diagnosis is increasingly achievable without invasive myocardial biopsy.
• Advances support tailored risk stratification, prognosis, and treatment strategies.

Conclusions:

• Recent diagnostic progress enhances the ability to determine the specific etiology of LVH.
• Non-invasive diagnostic approaches are becoming standard for managing LVH patients.
• Improved etiological diagnosis leads to optimized patient care and outcomes for left ventricular hypertrophy.