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Updated: Feb 3, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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[HIV-associated haematological complications].

L Seyler1, S Henrard2, J C Goffard2

  • 1Interne Geneeskunde, UZ Brussels.

Revue Medicale De Bruxelles
|October 16, 2018
PubMed
Summary
This summary is machine-generated.

Human immunodeficiency virus (HIV)-associated hematologic issues persist despite combined antiretroviral therapy. Certain lymphomas remain common, and non-neoplastic conditions still occur in HIV patients.

Keywords:
HIVHaematologyLymphoma

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Area of Science:

  • Hematology
  • Infectious Diseases
  • Oncology

Background:

  • Combined antiretroviral therapy (cART) has improved HIV prognosis.
  • HIV-associated hematologic complications remain frequent.
  • Some lymphoma incidence decreased, but diffuse B-cell and Hodgkin lymphomas persist.

Purpose of the Study:

  • To review persistent HIV-associated hematologic complications.
  • To discuss current treatment approaches for HIV-related lymphomas.
  • To highlight ongoing non-neoplastic hematologic issues in HIV infection.

Main Methods:

  • Literature review of HIV-associated hematologic complications.
  • Analysis of lymphoma incidence trends pre- and post-cART.
  • Discussion of non-neoplastic hematologic disorders in HIV.

Main Results:

  • Diffuse B-cell and Hodgkin lymphomas remain frequent in HIV patients.
  • Lymphoma treatments are now consistent for HIV-positive and negative individuals.
  • Immune thrombocytopenic purpura, thrombotic microangiopathies, and hemophagocytic lymphohistiocytosis are still linked to HIV.

Conclusions:

  • Hematologic complications continue to be a significant concern in HIV infection.
  • While cART has advanced HIV care, vigilance for hematologic issues is crucial.
  • Further research and management strategies are needed for these persistent complications.