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Perinatal risk factors for obstructive sleep apnea syndrome in children

Yafei Tan1, Dan Zhang1, Hui Mei1

  • 1Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, No. 100 Hongkong Road, Jiangan District, Wuhan, China.

Sleep Medicine
|October 16, 2018
PubMed

Insights

Specific perinatal factors like preterm birth and cesarean delivery are linked to childhood obstructive sleep apnea syndrome (OSAS). Maternal smoking and older maternal age also increase OSAS risk in children.

Area of Science:

  • Pediatrics
  • Sleep Medicine
  • Public Health

Background:

  • Obstructive sleep apnea syndrome (OSAS) is a prevalent condition in children.
  • Identifying risk factors for pediatric OSAS is crucial for early diagnosis and intervention.

Purpose of the Study:

  • To investigate the association between specific perinatal factors and the development of obstructive sleep apnea syndrome in children.

Main Methods:

  • A retrospective case-control study involving 823 children diagnosed with OSAS and 823 matched controls.
  • Logistic regression models were employed to analyze perinatal risk factors.

Main Results:

  • Preterm birth, cesarean section, and maternal smoking were significantly associated with increased risk of childhood OSAS.
  • Advanced maternal age (≥35 years), manual labor, and suburban living also increased OSAS risk.
  • Multiparous mothers showed a decreased risk of childhood OSAS.

Conclusions:

  • Perinatal factors play a significant role in predicting childhood OSAS.
  • Findings highlight key factors for physicians to consider in diagnosing pediatric OSAS.
Abstract

Keywords:
OSASPerinatal factorsPreterm birthsSleep disordered breathing

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