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Updated: Feb 3, 2026
Ultrasound-guided Transthoracic Intramyocardial Injection in Mice
Published on: August 5, 2014
A novel technique for iatrogenic pseudoaneurysm obliteration with ultrasound-guided thrombin foam injection
Paweł Lewandowski1, Jakub Baran1, Paweł Maciejewski1
11 Department of Cardiology, Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland.
Background:
Iatrogenic pseudoaneurysms (IPA) are treated with ultrasound-guided thrombin injections (UGTI). We describe a novel technique for IPA repair that applies UGTI with thrombin foam (UGTFI).
Methods And Results:
Successful obliteration of 6 IPAs (IPA without a neck, n = 5; with a neck, n = 1) in 6 patients (2 males, aged 68 ± 1 years, 4 females, aged 59 ± 11 years) was performed by using UGTFI. The dose of administered thrombin was 25-75 IU. No microembolization phenomenon and no serious clinical complications were observed.
Conclusions:
Treatment of IPA with UGTFI may reduce the embolization rate, risk of IPA cavity thrombin leakage, required drug dose. Use of the thrombin foam could be the next step in the development of the UGTI, particularly in the treatment of IPA without a neck.
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