From paper to practice: Strategies for improving antibiotic stewardship in the pediatric ambulatory setting

Michael J Bozzella1, Nada Harik1, Jason G Newland2

  • 1Division of Infectious Diseases, Children's National Health System, George Washington School of Medicine and Health Sciences, United States.

Insights

Antibiotic stewardship programs improve patient outcomes and reduce resistance by optimizing antibiotic use in outpatient settings. Strategies include education, algorithms, and feedback for better prescribing practices.

Area of Science:

  • Medical Science
  • Public Health
  • Pharmacology

Background:

  • Antibiotic stewardship is crucial for improving patient outcomes, combating antibiotic resistance, and reducing healthcare costs.
  • The majority of antibiotic prescriptions in the U.S. occur in ambulatory care settings, highlighting the need for effective stewardship interventions.

Purpose of the Study:

  • To review evidence-based strategies for enhancing antibiotic prescribing in ambulatory care.
  • To provide pediatric providers with practical approaches to implement antibiotic stewardship.

Main Methods:

  • The review summarizes various evidence-based strategies.
  • Methods include education for patients and clinicians, communication training, treatment algorithms, delayed prescribing, provider feedback, commitment letters, and justification prompts.

Main Results:

  • Multiple strategies have demonstrated effectiveness in improving antibiotic prescribing.
  • Tailoring interventions to practice workflows and culture is essential for successful implementation.
  • Combining multiple interventions maximizes impact.

Conclusions:

  • Effective antibiotic stewardship in ambulatory care requires a multi-faceted approach.
  • Pediatric providers can implement these strategies to optimize antibiotic use.
  • Continuous evaluation and adaptation of stewardship interventions are necessary.

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

Overview
59.9K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.5K
Setting Time of Cement01:12

Setting Time of Cement

The setting time of cement refers to the process of cement paste transitioning from a plastic state to a solid state. This process is crucial in construction as it dictates the timeframe for concrete placement, compaction, and finishing. The onset of this solidification is termed the initial set, indicating when the paste becomes unworkable. The final set is when the paste has solidified completely, and further handling or manipulation can no longer affect its shape. The cement strength is...
678
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
262
Characteristics of Practical Op Amps01:16

Characteristics of Practical Op Amps

A difference amplifier, a crucial component in numerous electronic devices, ideally amplifies only the difference-mode signal, which is the difference between two input signals. However, in practical circuits, the output voltage depends on both the differential gain and the common-mode gain.
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
864
Theoretical Foundations of Nursing Practice01:30

Theoretical Foundations of Nursing Practice

Theories play an essential role in organizing patient care. Theories refer to a proposed or followed belief, policy, or procedure that is the basis for action. Nursing theories are knowledge-based concepts that guide nurses' actions, influence nursing education and practice, and allow nurses to care for their patients.
Theories provide a perspective to assess patients' conditions and organize data and methods. They also assist in analyzing and interpreting information. They represent a...
17.4K