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Adult Onset Henoch-Schonlein Purpura associated with a Metastatic Malignancy of Unknown Primary Origin
Therese Posas-Mendoza1,2,3, Dayna Lucuab-Fegurgur1,2,3, Jefferson Roberts1,2,3
1University of Hawai'i Internal Medicine Residency, Honolulu, HI (TP).
Abstract:
The cause of Henoch-Schonlein purpura, or IgA vasculitis, is largely unknown. It has been associated with infections, other rheumatologic triggers, and adverse drug reactions. Rarely, adult Henoch-Schonlein purpura is also associated with solid-tumor malignancies. We present the case of a 66 year-old woman who presented with Henoch-Schonlein purpura associated with a metastatic malignancy of unknown primary origin. We recommend that adult patients presenting with Henoch-Schonlein purpura, especially those with no identifiable trigger, receive age-appropriate work-up for potential malignancy.
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