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Published on: February 16, 2022
Effect of Betel (Areca) Nut Chewing on Fractional Exhaled Nitric Oxide: A Pilot Study
YiChieh Kuo1,2, Francis Fu-Sheng Wu1,2,3, YingChung Lee2
1Show Chwan Memorial Hospital, Changhua City, Taiwan.
Abstract:
Betel (areca) nuts are extensively chewed in many countries. This has been associated with respiratory symptoms. We aimed to determine whether betel nut chewing is associated with acute changes in fractional exhaled nitric oxide, a non-invasive marker of airway inflammation. Betel nut chewing resulted in an immediate significant decline in fractional exhaled nitric oxide levels that persisted for up to 180 minutes. This effect has to be taken into account in epidemiological studies, reference ranges, and patient preparation.
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