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Updated: Feb 3, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Intraoperative conversion during video-assisted thoracoscopy does not constitute a treatment failure†
Alex Fourdrain1, Florence De Dominicis1, Jules Iquille1
1Department of Thoracic Surgery, Amiens University Hospital, Amiens, France.
Video-assisted thoracoscopic surgery (VATS) for lung cancer with conversion to thoracotomy has similar safety to open surgery. VATS is preferred, even if conversion is needed, offering potential benefits without increased risk.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Video-assisted thoracoscopic surgery (VATS) is increasingly used for lung cancer resection.
- Intraoperative conversion to thoracotomy may be necessary during VATS procedures.
- The safety of VATS with conversion compared to open thoracotomy requires evaluation.
Purpose of the Study:
- To compare morbidity and mortality rates of VATS with conversion versus full VATS and open thoracotomy for anatomical lung cancer resection.
- To determine if the surgical approach is a risk factor for 90-day postoperative mortality.
Main Methods:
- Retrospective, single-center study of 610 patients undergoing anatomical pulmonary resection (January 2011-January 2017).
- Patients were divided into full VATS, VATS with conversion, and open thoracotomy groups.
- Propensity score adjustment was used to assess 90-day mortality and morbidity, controlling for confounding factors.
Main Results:
- VATS with conversion group had higher rates of comorbidities and early-stage tumors compared to open thoracotomy.
- No significant difference in 90-day postoperative mortality (5.4% VATS+conversion vs. 3.7% open thoracotomy; P=0.58).
- Similar morbidity rates were observed between VATS with conversion and open thoracotomy groups; surgical approach was not a risk factor for mortality.
Conclusions:
- VATS with intraoperative conversion to thoracotomy is a safe approach for anatomical lung cancer resection, with similar early postoperative morbidity and mortality to open thoracotomy.
- VATS should be the preferred approach, as it offers potential benefits and is not disadvantageous if conversion is required.
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