Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Abnormal Proliferation02:23

Abnormal Proliferation

5.2K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.2K
Respiratory System Abnormal Finding I: Inspection and Percussion01:30

Respiratory System Abnormal Finding I: Inspection and Percussion

831
Respiratory system abnormalities are a significant concern in healthcare due to their potential to indicate underlying severe conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, and pneumonia. These abnormalities can often be detected through physical examination methods like inspection and percussion.
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
831
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

886
In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
886
Structural Protein Function01:56

Structural Protein Function

30.0K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
30.0K
Cardiovascular System Abnormal Findings II: Auscultation01:25

Cardiovascular System Abnormal Findings II: Auscultation

608
Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
608
Respiratory System Abnormal Finding II: Palpation and Auscultation01:31

Respiratory System Abnormal Finding II: Palpation and Auscultation

1.5K
In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two Years of Menaquinone-7 Supplementation and Coronary Artery Calcification: A Randomized Clinical Trial.

JAMA cardiology·2026
Same author

Chronic effects of baroreflex activation therapy: a tale of the unexpected.

Journal of hypertension·2026
Same author

Quantifying skeletal muscle energy metabolism during exercise in heart failure with preserved ejection fraction using in vivo  31P magnetic resonance spectroscopy.

ESC heart failure·2026
Same author

Association of type 2 diabetes according to the number of cardiovascular risk factors within the recommended range with neuropathy - The Maastricht Study.

Diabetes research and clinical practice·2026
Same author

Characterization of participants with a disproportionate degree of hypertension-mediated organ damage: the Maastricht study.

Journal of hypertension·2026
Same author

Cardiovascular autonomic dysfunction is linked with arterial stiffness across glucose metabolism: the Maastricht study.

BMJ open diabetes research & care·2026

Related Experiment Video

Updated: Feb 3, 2026

Three-Dimensional Shape Modeling and Analysis of Brain Structures
05:33

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

7.6K

Prediabetes Is Associated With Structural Brain Abnormalities: The Maastricht Study.

Marnix J M van Agtmaal1,2, Alfons J H M Houben3,2, Vera de Wit3

  • 1Department of Internal Medicine, Maastricht University Medical Center+, Maastricht, the Netherlands marnix.van.agtmaal@mumc.nl.

Diabetes Care
|October 18, 2018
PubMed
Summary
This summary is machine-generated.

Structural brain abnormalities are linked to prediabetes and worsen with type 2 diabetes. Early glucose management may prevent brain diseases like dementia and stroke.

More Related Videos

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function
05:44

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

Published on: July 14, 2016

7.9K
Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy
06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

Published on: November 30, 2018

9.8K

Related Experiment Videos

Last Updated: Feb 3, 2026

Three-Dimensional Shape Modeling and Analysis of Brain Structures
05:33

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

7.6K
Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function
05:44

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

Published on: July 14, 2016

7.9K
Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy
06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

Published on: November 30, 2018

9.8K

Area of Science:

  • Neurology
  • Endocrinology
  • Radiology

Background:

  • Structural brain abnormalities are established risk factors for dementia, stroke, and depression in type 2 diabetes.
  • It remains unclear if these abnormalities manifest in the prediabetes stage.

Purpose of the Study:

  • To investigate the association between prediabetes, type 2 diabetes, and specific structural brain abnormalities.
  • Examined lacunar infarcts (LIs), white matter hyperintensities (WMHs), cerebral microbleeds (CMBs), and brain atrophy.

Main Methods:

  • Utilized data from 2,228 participants in the population-based Maastricht Study.
  • Assessed diabetes status via oral glucose tolerance test and brain imaging with 3 Tesla MRI.
  • Employed multivariable logistic and linear regression analyses.

Main Results:

  • Prediabetes and type 2 diabetes were associated with increased LIs and WMHs compared to normal glucose metabolism.
  • Both conditions correlated with reduced white matter volumes.
  • No significant association was found between prediabetes and gray matter volumes or CMBs.

Conclusions:

  • Structural brain abnormalities are present in prediabetes and progress with type 2 diabetes.
  • These findings suggest early dysglycemia treatment could prevent brain diseases in middle-aged individuals.