Related Experiment Video
Updated: Feb 3, 2026

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR
Published on: February 23, 2016
Time-Resolved Chemically Induced Dynamic Nuclear Polarization of Biologically Important Molecules
Olga B Morozova1,2, Konstantin L Ivanov1,2
1International Tomography Center, Institutskaya 3a, 630090, Novosibirsk, Russia.
Abstract:
In this work, we review the hyperpolarization technique named chemically induced dynamic nuclear polarization (CIDNP), focusing on the time-resolved variant of this method and its biological applications. We introduce the main principles of polarization formation in liquids at high magnetic fields, provided by the so-called spin sorting mechanism. Applications of CIDNP to studying fast reactions of short-lived free radicals of biologically important molecules are discussed, as well as the potential of the method to probe the structure and magnetic parameters of such radicals. We also explain the principles of protein CIDNP and discuss applications of time-resolved CIDNP to studies of protein structure and dynamics.
Related Concept Videos
Molecular Shape and Polarity
Nuclear Transmutation
Nuclear Fusion
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
Group Polarization
Non-nuclear Inheritance
Nuclear Export of mRNA

