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Updated: Feb 3, 2026

Direct Vagus Nerve Injection Protocol For Rats
Published on: March 14, 2025
Preservation of the vagus nerves in subtotal esophagectomy without thoracotomy
Eduardo Crema1, Júverson Alves Terra Júnior2, Marisa Carvalho Borges3
1PhD, Full Professor, Division of Digestive Surgery, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba-MG, Brazil. Conception of the study, analysis and interpretation of data, manuscript writing, critical revision.
Purpose:
To evaluate the outcome of transhiatal esophagectomy without thoracotomy and with preservation of the vagal trunks for the treatment of advanced megaesophagus.
Methods:
Between March 2006 and September 2017, it was performed 136 transhiatal esophagectomies without thoracotomy by laparoscopy, with preservation of the vagus nerves. All patients were evaluated pre and postoperatively for respiratory and nutritional aspects Post operatively, some surgical aspects were evaluated like radiology and endoscopy of the digestive tract.
Results:
Follow-up for 7 months to 12 years by clinical, radiologic, endoscopic and pH monitoring revealed satisfactory and encouraging outcomes of the procedure.
Conclusion:
The laparoscopic transhiatal esophagectomy is a feasible and safe technique with good postoperative outcomes.
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