Mandibular augmentation in dogs with hydroxylapatite combined with demineralized bone

This study investigates the tissue response in dogs to mandibular augmentation with hydroxylapatite (HA) combined with demineralized bone. Thirty mongrel dogs underwent ridge augmentation with 3 ml of HA alone (HAO), HA combined with autogenous bone (HAB), or HA combined with demineralized bone (HAD). Bone was not found in the HAO augmented ridges through 52 weeks; bone was found in the HAB augmented ridges by 12 weeks, and the HAD augmented ridges had bone formation after 26 weeks. This study demonstrates that demineralized bone can induce osteogenesis within the HA augmented dog ridge, but it is delayed when compared to HAB augmentations.