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Asthma medication usage is significantly reduced following bariatric surgery
Alfredo D Guerron1, Camila B Ortega2, Hui-Jie Lee3
1Department of Surgery, Division of Metabolic and Weight Loss Surgery, Duke University Health System, 407 Crutchfield St, Durham, NC, 27704, USA. daniel.guerron@duke.edu.
Surgical Endoscopy
|October 19, 2018
Summary
Bariatric surgery significantly reduces asthma medication use in obese patients, with reductions observed up to three years post-operation. This finding highlights the impact of weight loss on asthma management.
Area of Science:
- Pulmonary Medicine
- Bariatric Surgery
- Obesity Management
Background:
- Asthma affects millions, with a significant overlap in patients with obesity who experience poorer asthma control and increased healthcare utilization.
- Obesity is linked to reduced asthma therapy response and increased pulmonary symptoms, suggesting a need for effective weight management strategies.
Purpose of the Study:
- To investigate the impact of bariatric surgery (BS) on asthma medication usage in patients with obesity.
- To test the hypothesis that asthma medication requirements decrease following bariatric surgery.
Main Methods:
- Retrospective analysis of adult patients with obesity using asthma medication pre-operatively who underwent bariatric surgery.
- Data collected up to three years post-operation, analyzing changes in asthma medication counts using Poisson generalized linear mixed models.
- Evaluation of the effects of time and bariatric procedure type on medication usage.
Main Results:
- A significant reduction in asthma medication use was observed, starting at 27% at 30 days and reaching 46% at 3 years post-operation (p < 0.0001).
- No significant differences in medication reduction were found between different bariatric surgery procedure types.
- Increased pre-operative BMI and use of GERD medication were associated with higher asthma medication use.
Conclusions:
- Bariatric surgery leads to a significant and sustained decrease in asthma medication use for up to three years.
- These findings underscore the effectiveness of bariatric surgery in improving asthma control in patients with obesity.
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