A Survey of Web-Based Chemogenomic Data Resources
Rasel Al Mahmud1, Rifat Ara Najnin2, Ahsan Habib Polash1
1Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Methods in Molecular Biology (Clifton, N.J.)
|October 19, 2018
Summary
Chemogenomics, the study of drug effects on molecular systems, faces data challenges. This guide overviews web-based resources to help researchers collect chemogenomic datasets efficiently.
Area of Science:
- Chemogenomics
- Molecular Systems Biology
- Drug Discovery
Background:
- Chemogenomics is an emerging field studying chemical and drug effects on molecular systems.
- The rapid growth of chemogenomic data presents challenges in data mining due to variations in measurements, biases, and redundancy.
- Newcomers often find data acquisition and analysis tedious.
Purpose of the Study:
- To provide an overview of accessible web-based chemogenomic resources.
- To guide users in hands-on data collection for chemogenomic projects.
- To highlight the domains of applicability for various chemogenomic databases.
Main Methods:
- Literature review of existing web-based chemogenomic resources.
- Description of data accessibility and usability features.
- Categorization of resources based on their applicability and data types.
Main Results:
- Identification of several key web-based chemogenomic resources.
- Demonstration of how to access and utilize these resources for data collection.
- Discussion of the strengths and limitations of different data sources.
Conclusions:
- Accessible web-based resources can significantly aid researchers in acquiring chemogenomic datasets.
- A structured approach to data collection can overcome common challenges in the field.
- This overview serves as a practical guide for navigating chemogenomic data resources.
Keywords:
ChEBIChEMBLChemProtChemSpiderChemogenomic resourcesLigand-target dataPharmGKBPubChemSTITCHWorld Wide WebMore Related Videos
Related Concept Videos
Data Collection by Survey
9.1K
The systematic method of obtaining and analyzing accurate information of a population is called data collection. A survey is a standard method of data collection that involves collecting information from a target human population about their experience, opinion, or knowledge of a product, service, or process. The responses are recorded and interpreted. The most common survey examples are written questionnaires, face-to-face or telephonic conversations, focus groups, and electronic (e-mail or...
9.1K
Surveys
16.8K
Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
16.8K
Introduction to Surveying, Plane Surveying and Geodetic Surveys
1.0K
Surveying is the art and science of mapping the earth's surface. It involves measuring distances, angles in horizontal or vertical directions, and levels to understand the shape and size of land features. Surveying techniques are essential for various tasks, such as identifying the levels of a land area with reference to a specific point, and mapping undulations and water bodies.There are two main types of surveying: plane surveys and geodetic surveys. Plane surveys assume the earth is flat,...
1.0K
Short-distance Transport of Resources
17.7K
Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
17.7K
Errors and Mistakes in Surveying
697
Errors and mistakes in surveying refer to inaccuracies in measurements and data recording. The errors are deviations from the actual value caused by human sensory limitations, equipment flaws, or environmental effects. These errors are typically unintentional and can result from the inherent imperfections in the instruments used, atmospheric conditions, or the observer’s inability to perceive exact measurements. On the other hand, mistakes are caused by the surveyor's lack of...
697
Types of Surveys
365
Surveys are essential for marking property boundaries near water bodies. Different types of surveys are defined, each with its own function. Land surveys mark the property boundaries, while route surveys determine the position of properties on nearby highways. Topographic surveys create maps by capturing the three-dimensional features of the land. Hydrographic surveys focus on the shapes of underwater areas and the movement of streams through the properties. Mine surveys determine the relative...
365


