Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fundamentals of Nursing Process I01:27

Fundamentals of Nursing Process I

8.8K
The nursing process is the core of practice for every registered nurse to deliver holistic, patient-focused care. The following are the five steps in the nursing process.
8.8K
Fundamentals of Nursing Process II01:25

Fundamentals of Nursing Process II

5.6K
There are several characteristics related to delivering nursing care. One vital characteristic of the nursing process is that it can be used to protect nurses and justify the provided care. Productive use of the nursing process requires the knowledge and skills of nurses to assess and solve issues. Nurses should develop and strengthen their critical thinking skills and evidence-based nursing interventions to improve their skills in formulating nursing care plans. A well-defined approach to...
5.6K
Fundamental Attribution Error01:14

Fundamental Attribution Error

13.8K
According to some social psychologists, people tend to overemphasize internal factors as explanations—or attributions—for the behavior of other people. They tend to assume that the behavior of another person is a trait of that person, and to underestimate the power of the situation on the behavior of others. They tend to fail to recognize when the behavior of another is due to situational variables, and thus to the person’s state. This erroneous assumption is...
13.8K
Electrocardiogram Fundamentals01:28

Electrocardiogram Fundamentals

1.5K
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
1.5K
Fundamental Theorem of Calculus I01:23

Fundamental Theorem of Calculus I

75
Solving problems involving definite integrals requires a systematic approach that ensures clarity and efficiency. The first step is understanding the problem by identifying the calculated quantity, whether it involves accumulation, area, or a physical concept like force or probability. It is essential to recognize given conditions, such as the range of integration and any constraints that may affect the solution. Before computing, key properties of definite integrals should be analyzed to...
75
Fundamental Theorem of Algebra01:30

Fundamental Theorem of Algebra

276
The Fundamental Theorem of Algebra is central to the study of polynomial equations, asserting that every non-constant polynomial with complex coefficients has at least one complex zero. This means that a polynomial of degree n ≥ 1, written as:  with an ≠ 0, has at least one solution in the complex number system. Since the set of real numbers is a subset of complex numbers, this theorem applies equally to polynomials with real coefficients.Building on this result, the...
276

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oligoclonal B cell expansion and passenger fusion genes predict response to Nivolumab in recurrent ovarian cancer: phase II Kyoto trial.

Cancer immunology, immunotherapy : CII·2026
Same author

Comprehensive Colorectal Cancer Stem Cell Transcriptomic Signatures That Can Predict Patient Prognostic Outcomes.

Cancer science·2025
Same author

A population-centered model for public health medicine.

Public health·2024
Same author

pyPept: a python library to generate atomistic 2D and 3D representations of peptides.

Journal of cheminformatics·2023
Same author

On the Medical Properties of Nitrate of Soda.

The North-Western medical and surgical journal·2023
Same author

Mutation burden-orthogonal tumor genomic subtypes delineate responses to immune checkpoint therapy.

Journal for immunotherapy of cancer·2022
Same journal

Isolation of Mesenchymal Stem Cell-Derived Extracellular Vesicles.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Modeling Melanoma Immune Surveillance by CAR-T Cells in Human Skin Organoids.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Stepwise Optimization of a Matrigel-Based In Vitro Angiogenesis Assay for Reproducible and Quantifiable 2D-Tube Formation Using HUVECs.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Quantifying Mechanical Properties of Fresh Ovarian Tissue with Optical Brillouin Microscopy.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

3D Chromatin Architecture During Early Development: New Methods and New Findings.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Metabolic Plasticity in Embryogenesis Throughout the Lens of NAD<sup></sup>.

Methods in molecular biology (Clifton, N.J.)·2026
See all related articles

Related Experiment Video

Updated: Feb 3, 2026

Data Communication Based on MQTT in a Polymer Extrusion Process
08:15

Data Communication Based on MQTT in a Polymer Extrusion Process

Published on: July 15, 2022

3.8K

Fundamental Bioinformatic and Chemoinformatic Data Processing.

J B Brown1

  • 1Life Science Informatics Research Unit, Laboratory of Molecular Biosciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. jbbrown@kuhp.kyoto-u.ac.jp.

Methods in Molecular Biology (Clifton, N.J.)
|October 19, 2018
PubMed
Summary
This summary is machine-generated.

This chapter explains standard data formats for computational chemogenomics. It provides a step-by-step guide to processing compound and protein data for advanced analysis and pattern discovery.

Keywords:
Chemical data structureCompound–protein visualizationDatabase retrievalMolecular data processing toolsProtein data structure

More Related Videos

Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research
08:12

Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research

Published on: February 16, 2024

15.7K
Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth
13:11

Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth

Published on: May 20, 2010

13.1K

Related Experiment Videos

Last Updated: Feb 3, 2026

Data Communication Based on MQTT in a Polymer Extrusion Process
08:15

Data Communication Based on MQTT in a Polymer Extrusion Process

Published on: July 15, 2022

3.8K
Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research
08:12

Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research

Published on: February 16, 2024

15.7K
Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth
13:11

Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth

Published on: May 20, 2010

13.1K

Area of Science:

  • Computational chemistry
  • Cheminformatics
  • Bioinformatics

Background:

  • Advanced computational chemogenomic workflows require understanding basic data formats.
  • Standardized compound and protein representations are crucial for data processing.

Purpose of the Study:

  • To explain de facto standards for compound and protein representation.
  • To provide procedures for processing these data formats.
  • To demonstrate a practical workflow for data acquisition and preparation.

Main Methods:

  • Downloading ligand-target databases.
  • Parsing bioactivity data.
  • Automated retrieval of chemical structures and protein sequences via command line.
  • Conversion of structures and sequences into machine-ready formats.
  • Visualization of parsed databases for pattern identification.

Main Results:

  • A comprehensive walkthrough of data processing steps.
  • Demonstration of automated data retrieval and format conversion.
  • A protocol for visualizing data to identify patterns.

Conclusions:

  • Understanding and processing standard data formats is essential for advanced computational chemogenomic studies.
  • The provided methods facilitate efficient data handling for machine learning and pattern discovery.