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Remodeling the neck and the lower jaw with dehoxycholate injections
R Rauso1, G Tartaro1, L Rugge1
1Maxillo-Facial Department, University of Campania "Luigi Vanvitelli", Naples, Italy.
Journal of Biological Regulators and Homeostatic Agents
|October 19, 2018
Summary
Off-label deoxycholic acid injections effectively remodel the neck and jawline in 18 patients. Personalized protocols led to aesthetic improvements with minimal, transient side effects, suggesting promising results for facial rejuvenation.
Area of Science:
- Aesthetic Medicine
- Dermatology
- Cosmetic Surgery
Background:
- Nonsurgical cosmetic facial procedures, or facial rejuvenation, are increasingly popular.
- Procedures targeting the neck and lower jaw for aesthetic enhancement are less common.
- Deoxycholic acid (DC) is approved for submental fat reduction but used off-label here.
Purpose of the Study:
- To evaluate the efficacy and safety of off-label deoxycholic acid (DC) injections for neck and lower jaw remodeling.
- To assess patient outcomes and side effects associated with personalized DC injection protocols.
Main Methods:
- Retrospective review of 18 patients undergoing off-label deoxycholic acid (DC) injections for neck and lower jaw contouring.
- Personalized injection protocols with premixed lidocaine and DC.
- Minimum 3-month follow-up post-initial injection, with consideration for further sessions after 3 months.
Main Results:
- Aesthetic enhancement of jaw and neck shape and contour was achieved in most patients.
- Documented side effects, including swelling and dysesthesia, were transient and resolved spontaneously.
- Only 2 out of 18 patients required a second injection session.
Conclusions:
- Personalized off-label deoxycholic acid (DC) injections can yield favorable aesthetic outcomes for neck and lower jaw remodeling.
- The treatment appears safe, with manageable and self-resolving side effects.
- Further investigation is warranted due to promising results and a small sample size.
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