Technology Development for Simultaneous Wearable Monitoring of Cerebral Hemodynamics and Blood Pressure

Area of Science:

• Biomedical Engineering
• Neuroscience
• Medical Devices

Background:

• Cerebrovascular diseases necessitate monitoring of blood pressure (BP) and hemodynamic changes.
• Current methods often lack simultaneous, high-temporal-resolution monitoring of these key variables.

Purpose of the Study:

• To develop and validate a novel, noninvasive system for simultaneous monitoring of cerebral hemodynamics and BP.
• To achieve high temporal resolution (250 Hz) for capturing dynamic physiological events.

Main Methods:

• Utilized near-infrared spectroscopy (NIRS) for cerebral hemodynamics.
• Employed superficial temporal artery tonometry with pulse transit time for continuous BP monitoring.
• Developed integrated sensors, monitoring system, and data analysis algorithms for a prototype device.

Main Results:

• Successfully demonstrated simultaneous, noninvasive recording of cerebral hemodynamics and BP during daily activities.
• Captured dynamic BP and hemodynamic fluctuations during postural changes and micturition.
• Preliminary tests confirmed the feasibility and utility of the developed approach.

Conclusions:

• The novel approach enables simultaneous, noninvasive monitoring of cerebral hemodynamics and BP.
• This technology has unique potential for analyzing transient symptoms like syncope and associated dynamic events.
• Feasibility is established for real-time physiological monitoring in daily life settings.