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An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Adaptation and Initial Validation of Minimum Data Set (MDS) Mortality Risk Index to MDS Version 3.0
Joshua D Niznik1,2,3, Song Zhang1, Maria K Mor1,4
1Center for Health Equity Research and Promotion, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.
The adapted Minimum Data Set (MDS) Mortality Risk Index-Revised version 3.0 (MMRI-v3) accurately predicts 6-month mortality in veterans. Combining MMRI-v3 with limited life expectancy (LLE) offers the best prediction for veteran mortality risk.
Area of Science:
- Gerontology
- Health Services Research
- Clinical Epidemiology
Background:
- Accurate prediction of mortality risk is crucial for clinical decision-making and resource allocation in nursing home settings.
- The Minimum Data Set (MDS) Mortality Risk Index-Revised (MMRI-R) has been used to predict mortality, but an updated version based on MDS version 3.0 (MMRI-v3) is needed.
- Identifying residents with limited life expectancy (LLE) is important for palliative care planning.
Purpose of the Study:
- To evaluate the predictive validity of the MMRI-v3 for 6-month mortality in veterans.
- To compare the predictive validity of the MMRI-v3 with a single MDS item indicating LLE.
- To assess the combined predictive ability of MMRI-v3 and the LLE indicator.
Main Methods:
- Retrospective, cross-sectional study utilizing MDS assessments from Veterans Affairs (VA) nursing homes.
- Included veterans aged 65 and older newly admitted between July 2012 and September 2015.
- Dependent variable: death within 6 months. Independent variables: MDS items for MMRI-v3 and LLE indicator.
Main Results:
- The MMRI-v3 demonstrated strong predictive ability for 6-month mortality (c-statistic 0.81), comparable to the original MMRI-R (c-statistic 0.76).
- MMRI-v3 showed superior predictive ability compared to the single LLE indicator (c-statistic 0.76).
- Combining MMRI-v3 with the LLE indicator yielded the highest predictive ability (c-statistic 0.86).
Conclusions:
- The MMRI-v3 is a valuable tool for predicting 6-month mortality in VA nursing home residents.
- The MMRI-v3 and LLE indicator are useful for research on palliative care interventions.
- These tools can aid in guiding the allocation of palliative care services in clinical practice.
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