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An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment
Published on: April 20, 2018
[Assessment of a digestive malabsorption syndrome]
J De Flines1, E Louis2, N Paquot1
1Service de Diabétologie, Nutrition et Maladies métaboliques, CHU Liège, Belgique.
Abstract:
Malabsorption syndrome is a complex clinical entity that needs to be carefully explored. Patients present frequently chronic diarrhoea associated with weight loss. These symptoms affect patient's quality of life. The assessment of this syndrome requires a detailed anamnesis, a careful clinical exam, the use of biological measurements in both blood and faeces, and, if necessary, other more complex investigations including radionuclide tests. It is important to find the right pathogenesis in order to start effective treatments if possible. First, there are classical bowel pathologies like celiac disease and rarely Crohn disease. Second, biliopancreatic pathologies may also result in a malabsorption syndrome. Of note, this syndrome is very common after abdominal surgery like intestinal resection following mesenteric ischemia, biliopancreatic and gastric surgery. We will use a clinical case of malabsorption after an abdominal surgery to illustrate how to explore these patients who are suffering from malabsorption.
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