[The evaluation of paroxysmal events in neonates and infants]

Eszter Nagy1, Nelli Farkas2, Katalin Hollódy1

  • 1Pécsi Tudományegyetem, ÁOK-KK, Gyermekgyógyászati Klinika, Neurológiai Tanszék, Pécs.

Ideggyogyaszati Szemle
|October 19, 2018
PubMed

Insights

Diagnosing infantile seizures by sight alone is difficult. Neonatologists and pediatric neurologists showed similar accuracy in identifying paroxysmal events, highlighting the need for video-EEG for accurate diagnosis.

Area of Science:

  • Pediatric Neurology
  • Neonatology
  • Clinical Neuroscience

Background:

  • Differentiating neonatal and infantile seizures based solely on visual inspection presents a significant diagnostic challenge, even for experienced specialists.
  • Paroxysmal events in infants require careful evaluation to distinguish epileptic from non-epileptic causes.

Purpose of the Study:

  • To investigate the diagnostic accuracy of various medical professionals in evaluating neonatal and infantile paroxysmal events based only on visual inspection.
  • To determine if there are differences in the assessment of common infantile paroxysmal events among neonatologists, pediatric neurologists, and neurologists.

Main Methods:

  • Video recordings of paroxysmal movements in 15 neonates and infants (2 days to 5 months old) were presented to 47 pediatric neurologists, 35 neonatologists/nurses, and 43 neurologists.
  • Participants assessed events as epileptic or non-epileptic without access to patient history or electroencephalogram (EEG) results.

Main Results:

  • Neonatologists and pediatric neurologists achieved similar correct diagnosis rates of 67% (824/1230).
  • Significant diagnostic uncertainty was observed for subtle hand movements and rapid clonus, correctly identified by only one-third of participants.
  • Neurologists' performance was slightly, but not significantly, different from that of pediatric neurologists.

Conclusions:

  • Accurate diagnosis of neonatal and infantile paroxysmal events typically necessitates video-electroencephalogram (EEG) recordings.
  • No significant difference was found between neonatologists and pediatric neurologists in their evaluation of infantile movement disorders.
  • Established collaboration between pediatric neurologists and neurologists supports a unified approach to diagnosing these events.
Abstract

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