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Determination of Plasma Membrane Partitioning for Peripherally-associated Proteins
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Plasma Protein Binding of Highly Bound Drugs Determined With Equilibrium Gel Filtration of Nonradiolabeled Compounds

John Isbell1, Ding Yuan1, Leonel Torrao2

  • 1Discovery Chemistry, Genomics Institute of the Novartis Research Foundation, Metabolism and Pharmacokinetics, San Diego, California 92121.

Journal of Pharmaceutical Sciences
|October 19, 2018
PubMed

Keywords:
HPLCalbuminalpha 1-acid glycoproteinliquid chromatography-mass spectrometry (LC-MS)protein bindingscintillation spectrometry

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