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MR Imaging in Menière Disease: Is the Contact between the Vestibular Endolymphatic Space and the Oval Window a

G Conte1, L Caschera2, S Calloni2

  • 1From the Neuroradiology Unit (G.C., E.S., C. Sina, F.T.), Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy giorgioconte.unimed@gmail.com.

AJNR. American Journal of Neuroradiology
|October 20, 2018
PubMed
Abstract

Insights

A new MR imaging sign, the vestibular endolymphatic space contacting the oval window, shows high accuracy in diagnosing Menière disease. This finding offers a reliable imaging marker for differentiating Menière disease from other conditions.

Area of Science:

  • Radiology
  • Otolaryngology
  • Neuroimaging

Background:

  • Menière disease diagnosis lacks reliable MR imaging markers.
  • Investigating novel MR imaging signs for Menière disease is crucial.

Purpose of the Study:

  • To evaluate the vestibular endolymphatic space contacting the oval window as a diagnostic MR imaging marker for Menière disease.

Main Methods:

  • Retrospective analysis of 49 patients (24 sudden hearing loss, 25 Menière disease) using 4-hour delayed 3D-FLAIR MR imaging.
  • Two readers assessed the vestibular endolymphatic space contacting the oval window sign.

Main Results:

  • The vestibular endolymphatic space contacting the oval window demonstrated high interobserver agreement (Cohen κ = 0.87).
  • This sign showed 81% sensitivity and 96% specificity in differentiating Menière disease from other conditions.
  • High positive predictive value (88-96%) was observed for this MR imaging marker.

Conclusions:

  • The vestibular endolymphatic space contacting the oval window is a specific and valuable MR imaging marker for Menière disease.
  • This sign aids in ruling in Menière disease, especially in cases with overlapping symptoms.

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