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Other Nuclides: 31P, 19F, 15N NMR01:16

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Many organic, inorganic, and biological molecules contain spin-half nuclei such as nitrogen-15, fluorine-19, and phosphorus-31. As a result, NMR studies of these nuclei have found extensive applications in chemical and biological research.
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An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
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15 years experience in proctological day-surgery.

Angelo Guttadauro, Matteo Maternini, Giulia Lo Bianco

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    Day-surgery is a viable option for proctological procedures, even complex ones, when patients are carefully selected and managed with local-regional anesthesia. This approach reduces hospital stays and associated risks, facilitating an earlier return to daily activities.

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    Area of Science:

    • Colorectal Surgery
    • Anesthesiology
    • Surgical Outcomes

    Background:

    • High hospitalization costs drive interest in reducing hospital stays.
    • Day-surgery offers patient benefits like reduced inconvenience and infection risk.
    • Proctological day-surgery is uncommon due to concerns about complications.

    Purpose of the Study:

    • To evaluate the feasibility and safety of day-surgery for proctological procedures.
    • To demonstrate the effectiveness of local-regional anesthesia in this context.
    • To share 15 years of experience in performing complex proctological procedures in a day-surgery setting.

    Main Methods:

    • Patient selection criteria: ASA I or II classification.
    • Performed 2688 proctological procedures between 2005 and 2015.
    • Utilized local anesthesia and perineal posterior block for pain management.

    Main Results:

    • 1062 procedures under local anesthesia had no significant complications; patients discharged within 2-3 hours.
    • Perineal posterior block in 932 patients provided optimal pain control in 51.6%.
    • 5.7% of patients required additional intravenous Fentanyl for pain management.

    Conclusions:

    • Day-surgery is achievable for proctological procedures with careful patient selection and technique.
    • Modified loco-regional anesthesia techniques enable complex procedures and same-day discharge.
    • Effective pain management and postoperative monitoring are crucial for successful day-surgery outcomes.