Related Experiment Video
Updated: Feb 3, 2026

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
Published on: April 4, 2016
A Genome-wide View of Transcriptome Dynamics During Early Spike Development in Bread Wheat
Yongpeng Li1, Xing Fu2, Meicheng Zhao1
1State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Shijiazhuang, 050021, China.
Wheat spike development involves coordinated gene expression, with auxin signaling increasing and cytokinin signaling decreasing. Key transcription factors (TFs) and genes like Eps-3 are identified, crucial for meristem development.
Area of Science:
- Plant Biology
- Molecular Genetics
- Developmental Biology
Background:
- Wheat spike development is a complex process involving cell proliferation and differentiation.
- The dynamic changes in gene expression during wheat spike development are not fully understood.
Purpose of the Study:
- To investigate the underlying regulatory mechanisms of bread wheat spike development.
- To identify key genes and pathways involved in early spike development.
Main Methods:
- Genome-wide gene expression profiling of wheat spikes across six developmental stages.
- Analysis of differentially expressed genes (DEGs), including transcription factors (TFs).
Main Results:
- High gene expression correlations suggest a small gene subset controls early spike development.
- Auxin signaling increased, while cytokinin signaling decreased during development.
- Genes related to stress responses were highly expressed during the double ridge stage.
- Identified 375 TF genes, with homologs in other species involved in meristem and floral development.
- The gene Earliness per se 3 (Eps-3) may function in spikelet meristem initiation.
Conclusions:
- Wheat spike development is regulated by specific gene expression patterns and hormonal signaling.
- Identified crucial transcription factors and genes, including Eps-3, that play roles in wheat apical meristem morphology and development.
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Genomics
Econometric Views (EViews)
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

