Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pneumocystis carinii infection.

P D Walzer

    Southern Medical Journal
    |November 1, 1977
    PubMed
    Summary

    Pneumocystis pneumonia (PCP) is a significant threat to immunocompromised individuals. While diagnosis and treatment have improved, further research is needed on its biology, host immunity, and reliable serologic tests.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A prognostic scoring tool for identification of patients at high and low risk of death from HIV-associated Pneumocystis jirovecii pneumonia.

    International journal of STD & AIDS·2011
    Same author

    Seasonal variation in mortality of Pneumocystis jirovecii pneumonia in HIV-infected patients.

    International journal of STD & AIDS·2010
    Same author

    Geographical variation in serological responses to recombinant Pneumocystis jirovecii major surface glycoprotein antigens.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2009
    Same author

    Human immunodeficiency virus-infected patients with prior Pneumocystis pneumonia exhibit increased serologic reactivity to several major surface glycoprotein clones.

    Clinical and vaccine immunology : CVI·2006
    Same author

    Anti-human immunodeficiency virus drugs are ineffective against Pneumocystis carinii in vitro and in vivo.

    The Journal of infectious diseases·2001
    Same author

    In vitro and in vivo effects of quinupristin-dalfopristin against Pneumocystis carinii.

    Antimicrobial agents and chemotherapy·2001

    Area of Science:

    • Medical Mycology
    • Infectious Diseases
    • Immunology

    Background:

    • Pneumocystis pneumonia (PCP) is a major opportunistic infection in immunocompromised hosts.
    • Significant advancements have been made in clinical recognition, diagnostic techniques, and therapeutic strategies for PCP over the last decade.

    Purpose of the Study:

    • To highlight the progress in understanding and managing Pneumocystis infections.
    • To identify critical knowledge gaps in the biology, taxonomy, epidemiology, and host immune response related to Pneumocystis.
    • To emphasize the need for a reliable serologic test for clinical use.

    Main Methods:

    • Review of recent literature on Pneumocystis carinii research.
    • Analysis of clinical awareness, diagnostic methods, and treatment advancements.
    • Identification of areas requiring further investigation.

    Main Results:

    • Clinical awareness, diagnosis, and treatment of PCP have improved.
    • Substantial gaps remain in understanding Pneumocystis biology, taxonomy, and epidemiology.
    • Knowledge regarding specific host immune factors in PCP pathogenesis is limited.
    • A clinically reliable serologic test for Pneumocystis is still lacking.

    Conclusions:

    • Despite progress, fundamental knowledge gaps concerning Pneumocystis persist.
    • Further research is crucial to elucidate the organism's biology, host interactions, and to develop better diagnostic tools.
    • Future advancements in Pneumocystis research are anticipated to address these critical areas.

    Related Experiment Videos